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A permanent and personalized solution for epileptic seizures that cannot be controlled with medication.

What is Epilepsy?

Epilepsy is a disease characterized by recurrent seizures caused by abnormal electrical discharges in the brain. While some types of epilepsy can be controlled with medication, seizures persist in refractory epilepsy. In these cases, surgery may offer the patient the chance to live a seizure-free life.

What is Refractory (Drug-Resistant) Epilepsy?

  • Persistence of seizures despite at least two appropriate antiepileptic drugs

  • Seizures are of such frequency and severity that they affect daily life.

  • MRI, EEG and clinical data show a focal point

  • In these cases, you may be a candidate for epilepsy surgery.

Image of "What is refractory epilepsy? Epileptic seizures that do not respond to medication"
Visual representation of the goal of epilepsy surgery, controlling seizures, improving quality of life and preserving brain function

What is the Goal in Epilepsy Surgery?

Our goal is to remove or neutralize the epileptic focus (the area where the seizure begins) without damaging the functional areas of the brain. Thus:

  • Seizure frequency and severity are reduced

  • Complete seizure control (seizure-free) can be achieved

  • The number and dosage of medications can be reduced

  • Quality of life improves significantly

Diagnostic Process Leading to Surgery

Each patient is evaluated by a multidisciplinary epilepsy council. Necessary tests include:

  • Video-EEG monitoring: Determining the source of the seizure

  • Magnetic Resonance (MRI): Is there a lesion? (e.g. Focal Cortical Dysplasia, hippocampal sclerosis)

  • PET, SPECT: Functional imaging if no lesion is seen

  • Neuropsychological tests: Memory, attention, speech functions

  • fMRI or WADA testing: Mapping functional areas

Image of Determination of the focus of epilepsy with EEG, video-EEG monitoring, MRI and neuropsychological tests
Image showing the surgical methods we use in epilepsy surgery, temporal lobectomy, lesionectomy, calosotomy and vagus nerve stimulation (VNS)

Surgical Methods We Apply

  • Focal Resection / Lobectomy

Removal of the epileptic focus (e.g. temporal lobectomy)

  • Hemispherotomy

Disabling of one half of the brain (most often in children)

  • Subpial Transection / Corpus Callosotomy

Incisions that prevent seizure spread (in generalized seizures)

  • Vagal Nerve Stimulation (VNS)

Pacemaker implantation in the neck to reduce seizures in patients unfit for surgery

Post-Operative Process

  • Usually 3-4 days of hospital stay

  • EEG and neurological evaluation every 3–6 months

  • Medication reduction according to seizure control

  • Psychological support and rehabilitation support (in necessary cases)

  • Long-term follow-up

Visual showing the process after epilepsy surgery, seizure control, regular follow-up, medication adjustment and improving quality of life
Image showing suitable candidates for epilepsy surgery, patients with medication-resistant epilepsy, identified epilepsy focus, and appropriate neurological evaluation results

Who is a Suitable Candidate?

  • Those with epileptic focus detected on MRI (e.g. FCD, mesial temporal sclerosis)

  • Even if there is no lesion on MRI, those with focus determined by EEG/PET

  • Intractable seizures causing developmental delay in pediatric patients

  • Individuals with seizure frequency that disrupts daily life

Frequently Asked Questions (FAQ)

  • Will I be completely cured with surgery?
    Complete seizure freedom can be achieved in some patients. Success depends on the precise location of the seizure focus.

  • Will there be memory loss or speech impairment?
    These risks are minimal in surgeries performed without touching functional areas. If necessary, fMRI or WADA protection is provided.

  • Can surgery be performed on children?
    Yes, early surgery provides greater benefits, especially in children with developmental disabilities.

Operasyon Tiyatrosu
Second Opinion and Appointment

Deciding on epilepsy surgery requires expertise and an epilepsy team. If you have refractory epilepsy, please contact us for a second opinion or to evaluate your diagnosis.

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Neurosurgeon

Assoc. Prof. Dr. Alican Tahta

Address

Medipol Mega University Hospital

TEM European highway Göztepe exit no:1, 34214 Bağcılar/İstanbul

© 2025 by Alican Tahta

The content on our website is for informational purposes only and does not constitute medical advice. If you have any medical issues, please consult your doctor.

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